GARDEN PARTY OF ANNU & RASTAFARIAN PRIESTESSES, PRIESTS & CHILDREN (FROM SOCIAL LIFE IN ANCIENT
EGYPT, BY ALAN H. GARDINER, PG. 176, TOMB PAINTING OF NEFER-HETEP, THEBES, C. 1350 BC.
GARDEN PARTY OF ANNU & RASTAFARIAN PRIESTESSES, PRIESTS & CHILDREN (FROM SOCIAL LIFE IN ANCIENT
EGYPT, BY ALAN H. GARDINER, PG. 176, TOMB PAINTING OF NEFER-HETEP, THEBES, C. 1350 BC.
8b. THE ORIGINAL SICKNESS PREVENTION (OSP) PARADIGM::
THE PROBLEM OF THE AMERICAN HEALTH NATIONAL SECURITY ISSUE OMISSION: "THE GREAT RAMIFICATIONS OF DIETARY CHOLESTEROL AND BILE ACID METABOLISM"[All video clips are in the Real Media file format (rm) and can be played on the Real One Player, which can be freely downloaded from www.real.com. as part of a "14 day trial"; i.e. you can continue using the Real One Player even if you choose not to accept the "trial offered" packaged Real One Internet Media Service after 14 days.]
ENDORSEMENT:
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State of the World Forum Member # 20827 photo by Franz Louis (2010)
2007 & 2009 European Union Humanitaran Grantee
www.TheUniversityofGod.org Web Master
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CHRONIC POVERTY CAN BE ELIMINATED IN OUR LIFE TIMES.
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2007 EUROPEAN UNION HUMANITARIAN GRANTEE
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B. THE PROBLEM OF THE AMERICAN HEALTH NATIONAL SECURITY
ISSUE OMISSION: "THE GREAT PATHOPHYSIOLOGICAL RAMIFICATIONS
OF DIETARY CHOLESTEROL AND BILE ACID METABOLISM"
White/Blue/Red/Green Paper Series: American Health System
Policy Analysis and Synthesis
Abstract
This Web Page by America's 2007 & 2009 European Union Humanitarian Grantee BRCA, Inc.
points out that the 2009-10 historic public meeting debates and media analysis that finally led
to passage of Health Care Reform Legislation by the US Congress, predictably omitted the "Key
Health National Security Issue" that the major cause of the ever increasing health care costs in
America is the failure to address properly the complex etiology of the chronic diseases and
syndromes. The paramount role of Dietary Cholesterol in the etiology of the chronic diseases
and syndromes of the Heart, the Cancers, Stroke, Asthma, Emphysema, Bronchitis, Diabetes Mellitus, Alzheimer's, Influenza, Pneumonia, the Kidneys, the Liver, Hypertension,
Parkinson's and Septicemia was not addressed.
Additionally, as Amnesty International USA has identified in 2010 America's genocidal rate
of maternal mortality which also encompasses the associated excessive infant mortality rate
are in need of amelioration immediately especially in America's inner cities as genocide is occuring.
Astonishingly, this complex etiological causation of the chronic diseases and syndromes
is the same for the genocidal rates of maternal mortality and infant mortality; i.e. Dietary
Cholesterol and its related Animal Protein and Animal Fat residues acting as a slow blood poison
that simultaneously supports nutritionally a chronic colonic anaerobic bacterial toxemic infection
and chronic intestinal constipation generating blood transported organ inflammatory and
autoimmune reactions with cellular, tissue and organ necroses, mutagenesis and carcinogenesis.
The National Security relevance of this omitted health issue is based on the fact that the ancient
Roman Empire and the modern Great Britain Empire fell in large part from within ignoring this issue
of breaking the Law of Nature in regards the aboriginal natural Vegan (herbivore) Diet of human
beings presented in the Bible Genesis 1: 29 (King James Version):
"And God said, 'Behold, I have given you every herb bearing seed, which is upon
the face of all the earth, and every tree, in the which is the fruit of a tree yielding
seed; to you it shall be for meat'."
The ancient Athens, Greece located School of Sickness Treatment trained Greek "Father of Medical Writing" Hippocrates VI of Cos (460 BC to 377 BC) itself derived from the teachings of Ancient Egypt/Kemit Dynasty III Vizier and Physician Inhotep as taught him as student Priest by the School of On (God or Annu) wrote:
"Everyone has a doctor in him or her; we just have to help it in its work. The
natural healing force within each one of us is the greatest force in getting well.
Our food should be our medicine. Our medicine should be our food. But to eat
when you are sick, is to feed your sickness."
TABLE OF CONTENTS: WED PAGE 8 B
8b. THE ORIGINAL SICKNESS PREVENTION PARADIGM::
THE PROBLEM OF THE AMERICAN HEALTH NATIONAL
SECURITY ISSUE OMISSION:
"THE GREAT RAMIFICATIONS OF DIETARY CHOLESTEROL
AND BILE ACID METABOLISM"
TEXT SECTION
I. Introduction
II. Objective
III.
The American Health National Security (HNS) Omission of The
Great Pathophysiological Ramifications of Dietary
Cholesterol
& Bile Acids"
A. The Root Problems of the
American Health Care System
B. General Statistics National
C. Esoteric Existence of Iatrogenic Disease and Iatrogenic Poverty Morbidity and Death
D. The Background Noise of the Cancer Epidemic
E. The Top Fifteen Killers (TFK) of Americans in 1996, 2000 and 2006
IV. Etiology of Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)
A. Dietary Cholesterol is not a Dietary Requirement
B. Stereoisomer Specificity & Organic Steroid Chemistry of Cholesterol:
Natural-Cholesterol (5 cholesten 3-beta-ol)C. Colorectal Cancer Cause ID & Connection to America's High Fat Diet
TABLE OF CONTENTS (Continued): WED PAGE 8 C
8c. THE ORIGINAL SICKNESS PREVENTION PARADIGM::
THE SOLUTION OF THE AMERICAN HEALTH
NATIONAL SECURITY ISSUE OMISSION:
"THE GREAT RAMIFICATIONS OF DIETARY CHOLESTEROL
AND BILE ACID METABOLISM"
IV. Etiology of Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)
D. Secrets of Dietary Cholesterol and Bile Acid MetabolismE. The So-Called Amino Acid Taurine and Bile Acid Metabolism
F. The Cholesterol Reducing Drugs and the Metabolic SyndromeG. The Sanitation of the Human Body Blood Stream is the Key to Health
H. Great Britains Prince of Wales Charles Warning to United Arab Emeratus/
Abu Dhabi about the Etiology of Diabetes Mellitus
V. The American Cancer Society, American National Cancer Institutes AARP and European
Longitudinal Studies of Meat Intake and Mortality
VI. Misconceptions of Allopathic Medical Sciences, Education and Treatment
TABLES
I. Leading Causes of Death in USA in 1996, 2000 and 2006:: The Esoteric Top Fifteen Killers (TFK)
II. Fecal Endogenous & Dietary Cholesterol, Coprostanol, Primary & Secondary Bile Acids And Salts In Human
Omnivores, Vegetarians & Vegans (Herbivores)
III. Inventory of Mutagenic, Carcinogenic, Atherogenic and Toxogenic Agents Etiologically Implicated in Colorectal
Cancer, Heart Disease and other Chronic Diseases and Syndromes
IV. Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and
Syndromes (DCRDS): Results of the DCRDS Systems Analysis Body Flow Chart
V. DCRDS Prevention Education and Death Cause Averted and Money Save Annual
VI. Inventory of Toxic Bile Acids and Neutral Steriods Exposed to Fetuses, Neonatals and Infants
APPENDIXES
A-1. The Aboriginal Diet of Humans (Homo Sapiens)I. Ancient African, Eastern and Middle Eastern Cultures and Civilizations: Golden Age
II. Ancient European and North Asian Culture and Civilizations: Mammal Cannibalism
III. Origin of the Vegetarian Diets of Africa and Asia: Accommodation
IV. The Omnivore Diets Deleterious Effects Compounded by Allopathic Medicines: Metabolic Syndrome
A-2. The Aboriginal Christians were VegansI. Writings on the Jesus Christ Disciples as Vegans
II. Early Christian Clergy and Saints Testimony
III. Bible References: Vegan and Vegetarianism: Original Ideal and Ultimate Hope
IV. Bible References: God Cares Abount Animals and Wants Us to Care About Animals
V. Bible References: Animal Sacrifices Are Rejected by God
VI. Past and Present Notable Philosophers, Scientists and Authors Testimony
B. Bruno Meessen, PhD. et al, editorial Iatrogenic Poverty in Trop Med and Inter Hlth J, 8 (7) pp. 581- 4, 2003
C. Press Release and the Science Magazine, May 17, 2002 article by Makoto Makishima, PhD, et al,
"Vitamin D Receptor as an Intestinal Bile Acid Sensor
D. Izrael Hieger, D. Sc., article "Carcinogenesis by Cholesterol" in British Journal of Cancer, V. 8 (1), pp 439-451, 1959
E. Dean Ornish, MD. editorial "Mostly Plants" in Journal of American Cardiology, May, 2009
F. George W. Singleton, HD. Holistic Reversal of Alzheimers Disease and Parkingtons Disease Dementia, 2010
G. Jay M. Hoffman, PhD. book synopsis of the Hunza: 15 Secrets of the World's Healthiest and Oldest
Living People, 1985
H-1. George W. Singleton, HD. "Avoid the White Foods" extract from Original Prevention of Sickness:
General Nutrition Instructions (OPS), 1997, rev. 2005
H-2. George W. Singleton, HD. "The 12 Causes and Prevention of Cancer" extract from OPS, 1997, rev. 2005
I-1. Amnesty International, USA Citation of American Genocidal Maternal and Infant Mortality Rates, 3/2010
I-2. Global Maternal and Infant Death Rates Decrease while American Rates Genocidally Increase, 4/2010
I-3. Glantz, Anna, et al, article "Intrahepatic Cholestasis in Pregnancy: Relationships Between Bile Acid
Levels and Fetal Complication Rates" in Hepatology J, V 40, No. 2, pp 467-74, 2004
FLOW CHARTS
#1. George W. Singleton, HD. General Human Systems Theory (GHST) Poverty Systems Analysis--Detailed, 2005
#2. George W. Singleton, HD. The Dietary Cholesterol and Related Diseases (DCRDS) Human
Body Systems Analysis, 2009 (Hand Scribed in 5 colors)
B. The Problem of the American Health National Security Issue Omission:
"The Great Pathophysiological Ramifications of Dietary Cholesterol &
Bile Acid Metabolism"
TEXT
I. Introduction
As the 2007 and 2009 European Union Humanitarian Grantee in America the objectives of the United Nations Millennium Project of reducing extreme poverty within America and outside America are my objectives. Identifying the major cause of Iatrogenic Poverty and much of Economic Poverty as the suppressed and largely unknown, unaddressed and preventable nutritionally related illnesses is my paramount priority.
Consequently, it is my duty to point out humbly that the debate and documentation leading to the just passed American Health Care System Reform Legislation (Legislation) including the nation's health care system problem analysis, the projected costs and savings and the "100 Best Practices Research Topics" were epistemologically corrupted as the cause(s) of the chronic diseases and syndromes were not addressed. This is because it is a US "National Security (NS)" Issue and ideally and practically now requires a US Executive Branch NS Forum to properly resolve by necessity behind closed doors beyond special interest lobbyist tampering and the media promulgation until desired.
My Resume is linked to http://www.theuniversityofgod.org/ as the reader needs to know my academic and work background in the synthesis of rural health research methodology, poverty abatement adjudication, policy development and demonstrations and the practice for 30 years of "nutritional herbology" __the sickness treatment epistemological opposite to allopathic medicine __ to assess the iconoclastic material presented herein.
II. Objective
The objective of this Web Page is to verify for the reader that the "Health National Security Issue Omission" identified and detailed herein if acted upon properly can lead to achievable, documented quantified savings in their family and in the Nation's healthcare expenditures from subsequent properly directed sickness prevention education and practice incentives.
This would in turn lead to bipartisan support Health Care Reform Implementation. It is felt that the ignorance of this "Health National Security Issue Omission" by the general public as well as the opponents of the Health Care Reform Legislation can only be addressed effectively by its exposure because the shame of ignorance will disarm this issue as a November 2010 election issue again by necessity held initially behind closed doors with the same objective.
Is it possible for the US Congress to do the unexpected and have a bipartisan and overwhelming
majority of both parties implementing a modified American Health Care System Reform Legislation
that reflects this "Health National Security Issue Omission" based on an appropriately self-funding design and a "sickness prevention health education and practice incentives" implementation enrolling all Americans? Yes, if this request for the White House Office of Health Care to hold an appropriate American Maternal and Infant Mortality Etiology and Possible Solutions Forum is met!
III. The American Health National Security (HNS) Omission of The "Great Pathophysiological
Ramifications of Dietary Cholesterol & Bile Acids"
American clinical allopathic Medical Doctors (MDs) by definition are taught and use clinically an allopathic health care paradigm. In sickness treatment epistemological terms "allopathic" means a health care paradigm which targets primarily symptoms of a disease or syndrome in order to produce an opposite effect. The allopathic clinical MD's standard laboratory references include Todd, Stanford and Davidsons Clinical Diagnostic and Management by Laboratory Methods, 2 Volumes; and page 317 of its 1979 edition sums up this "National Security Health Issue Omission" best:
"The pathophysiological ramifications of bile acid metabolism are great and
beyond the scope of this chapter (or any chapter in the 2 Volume edition)."
As the Todd, Stanford and Davidson, Clinical Diagnostic and Management by Laboratory Methods represents the standard allopathic clinical physician paradigm medical lab reference; it is clear that most medical scientists, practicing physicians and other health care providers are unaware of this complicated medical science subject area. More succinctly for the vast majority of America's allopathic medical doctors, osteopathic physicians, dentists, nurses, dieticians, physical therapists and chiropractors the "metabolism of the primary bile acids," the metabolism of their precursor Dietary Cholesterol and the enteric bacterial degradation toxemia products of the misnomer "secondary bile acids" and the "tertiary bile acids" and "their great pathophysiological ramifications" are left out of their research and clinical education and training.
Instead American clinical MD.'s and other health practitioners are left with the symptomatic use of high tech health diagnostic electronics, prescription drugs, surgery including the transplant of dysfunctional organs, nuclear radiation and other allopathic medical procedures to address the proliferation of chronic diseases and syndromes. Because Dietary Cholesterol is involved in their independent risk factors they are called herein the Dietary Cholesterol and Related Diseases and Syndromes (DCRDS) that have gripped America in the last 30 years.
In other words, the chronic diseases and syndromes including the latest Metabolic Syndrome detailed below are "the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism" which are herein called the Dietary Cholesterol and Related Diseases and Syndromes (DCRDS). This Health National Security Issue has been suppressed for over 70 years from public knowledge and the Legislative debate by the allopathic physician lead medical industry and the Special Interest pharmaceutical, animal meat, fish, dairy and restaurant industries.
Note: The "politically correct" stance that those who know about the 70 year suppression of the "great pathophysiological ramifications of dietary cholesterol and bile acid metabolism"
and are trying to ameliorate the health care crisis it has spawned by citing its National
Security damage and danger to the American body politic are enemies of America is
not true. Such critics are not attacking the founding values of the American society and
economy but are opposed to the Special Interest industry profiteers "blood sucking"
the American people.
A. The "Root Problems" of the American Health Care System
The "root problems" of America's health care system go beyond private verses public health care insurance and the perennially increasing per capita cost of the health care industry that dominates
the public debate. These "root problems" are not public debate topics as they have been made ad hoc taboo and suppressed by Special Interest groups into National Security ones that are not to be talked about in the mass media.
It is declared herein that in the last 70 years the failure of the American allopathic medical research institutions and medical schools to conduct research, teach its students and communicate to the public the knowledge that "the great pathophysiological ramifications of dietary cholesterol and bile acids metabolism" are the key etiological elements in the "Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)" and leading ineviably to the present deteriorated health care status in America with the following "root problems:"
1.) The unbalanced allopathic medical epistemological foundation of the medical sciences,
the medical education and the health care industry which abuses human rights in
regards to legal cancer treatment options and so-called healthy "balanced meat diet
alternatives.
Note a.): The now deceased Vegetarian Mrs. Coretta King wife of Reverend Martin Luther
King had to illegally go to Mexico to get the alternative cervix cancer treatment
she desired.
Note b.): The majority of the allopathic and osteopathic physicians of elderly patients
including those with cancer in most states still advise the best diet is a
"balanced meat diet;" although all credible in vitro, in vivo and objective observational/epidemiological research clearly shows the aboriginal
Vegan Diet and less restrictive Vegetarian Diet as superior in lower disease
risk factor incidences, lower death rates, lower infant and maternal mortality
rates and longer life spans than the Omnivorous Diet.
2.) The proliferation of chronic diseases and syndromes which are in reality DCRDS where
50% of those who die of a non-cancerous disease when autopsied are also found to have had cancer __ the cancer epidemic background noise caused by the high fat and high protein modern American Omnivores Diet.
3.) Failure of the allopathic MD lead health care industry to prevent and control the chronic diseases and syndromes including the most recent Metabolic Syndrome attributable to
the ingestion of Dietary Cholesterol and related Animal Protein and Animal Fat residues
whose causative relationship has been suppressed for over 70 years and continues to be so.
Of notable exception is the allopathic medical specialty of cardiology as represented by the
iconoclastic nutritional science etiological statement by Dr. William C. Roberts, M.D., editor
of The American Journal of Cardiology who is quoted as follows:"When we kill the animals to eat them, they end up killing us because their
flesh, which contains cholesterol and saturated fat, was never intended
for human beings."
Again of notable exception is American cardiologist Dr. Dean Ornish, MD. whose "Reversal
Diet" allows only 5 mg of dietary cholesterol/day has been documented [Ornish, D.,
Scherwitz, L. W., Billings, J. H., Brown, S. E., Gould, K. L., Merritt, T. A. et al, "Intensive
lifestyle changes for reversal of coronary heart disease," JAMA, 1998, 280: 2001- 2007] to be
an authentic therapeutic diet capable of reversing the #1 killer of Americans cardiovascular
disease. Dr. Ornish's Preventative Diets are authentic cardiovascular disease preventive diets.
He attributes the foundational basis of his diets to his religious Hindu Hatha Yoga Master
Swami Satchidananda.
Please read Dr. Ornish's state of the art editorial Mostly Plants in the May, 2009 American
Journal of Cardiology included herein as Attachment E.
4.) Treating the symptom of high serum cholesterol levels caused by Dietary Cholesterol with expensive and potentially harmful prescription drugs that suppress "bad" (low density lipoproteins, LDL) cholesterol and increase "good" (high density lipoproteins, HDL) cholesterol objectively evaluated by sickness treatment epistemology is not the best efficient and effective treatment compared to the aboriginal sickness prevention approach of decreased eating of Dietary Cholesterol foods with the Vegetarian Diet or better abstaining from such "pseudo" foods containing "slow poisons" with the Vegan Diet.
Note: This issue is not even included in the 2009 federally mandated Institute Medicines 100 Initial Priority Topics for Comparative Effectiveness Research of the best practice questions as expected since this issue is being suppressed by the Special Interest lobbies of the meat, restaurant, pharmaceutical and health care industries.
Again the notable exception is Dr. Dean Ornish, MD., Director of the Preventive Medicine
Research Institute whose "Statins and the soul of medicine" editorial in the American
Journal of Cardiology, V. 89, pp. 1286-1290, June, 2002 takes issue with this questionable
drug therapy.
5.) The emergence of America's "actual" number 3 leading cause of death after heart diseases and the cancers of Iatrogenic Disease (caused by physicians and their health care system) resulting yearly on average 250,000 deaths and the driving force behind the perennially increasing and seemingly excessive malpractice insurance premiums practicing physicians must pay to protect themselves from legal torts (suits). [D 3]
6.) The unsustainability of the present American health care system being ineffective and
inefficient compared with other industrialized nations reflected in America having twice
the per capita health care costs in 2009 projected at $8,000/person compared to other
industrialized countries and yet producing a below average health status internationally
with 41 countries with longer Life Expectancies and 27 countries with lower Infant
Mortality Rates: This is embarrassing as many of these countries are developing
countries.
From sickness treatment epistemology this "Health National Security Issue Omission" of "the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism" is the root cause
of the unrelenting annual escalation of America's health care costs, the unrelenting failure to
produce significant improvement in morbidity and mortality rates, the excessive malpractice rates
and the 47 million Americans without access to primary health care.
In summary, the health care industry Special Interests including the allopathic and osteopathic
physicians and their medical research schools, pharmaceutical companies, insurance companies,
the meat industry, dairy industry, fish industry and restaurant industry have suppressed the
awareness of this Health National Security Issue for over 70 years.
B. General Statistics -- National
The American health care industry lead by the allopathic MDs is obviously performing inefficiently
and ineffectively looking at international comparisons of health care cost/benefit ratios and health
care status general statistics. The following general statistics indicate a crisis in health care of
National Security significance in America incapacitating and killing hundreds of thousands annually
that can be easily prevented and would extend millions of American lives, save billions of dollars
and significantly increase the nation's Gross National Product (GNP) to record per capita levels:
1.) Per Capita US Health Care Expenditures officially was $6,714 in 2006, more than twice
the average of other advanced countries. It is projected to be over $8,000 in 2009.
Note: Again there is a relationship between this high expenditure rate and the high
malpractice insurance rates American physicians must pay to practice. It is
believed the esoteric Iatrogenic Disease factor to be presented below plays
a significant role here.
2.) US Infant Mortality Rate (IMR) at 6.9% (per 1000 live births) as reported in 2008 by the US Center for Disease Control and Prevention (CDC) places America 29th in industrialized countries compared with Japan's IMR of 3.1% and 3 rd amongst industrialized nations. The IMR amongst African Americans at 16.7% is genocidal! See related 3.) below and Appendix I-1 and Appendix I-2.
Note a: The CDC in its 2008 Annual Report on the nation's Infant Mortality Rates pointed to the
lack of progress in infant mortality prevention from 2000 to 2006__ a lack of progress in
this vital health index not seen since the 1960's. America could once boast about its IMR
but has steadily lost its health status advantage internationally the last 30 years since
passage of the Civil Rights Bill.
Note b: This period from 2000 to 2006 coincides with: i.) the proliferation of the high fat and high
protein fast food restaurants in America; ii.) the unannounced substitution of the federally
subsidized productionof the higher caloric high fructose corn syrup for the lower caloric
sugar cane and sugar beet sucrose as a sweetener by America's refined food industry;
iii.) an attempt to corrupt medical science further with federal research using statistical
manipulation of death rates to give overweight and obese individuals longer life spans
than normal and underweight individuals; iv.) the appearance of the Metabolic Syndrome
[the cluster of cardiovascular and diabetic risk factors including visceral (waist)obesity,
high blood pressure, insulin resistance, elevated triglycerides and low HDL cholesterol];
and v.) the manifestation of the Metabolic Syndrome as a major dysfunction of the people.
Note c: In a disturbing finding the infant merconum (first bowel movement after birth) as well as
neonatal newly born infant bile and infant blood contains high amounts of 22-Hydroxy
Cholesterol, C-24 mono-hydroxy bile acids called 3-beta-hydroxy cholenoic acid and
Lithocholic acid which are dangerous co-mutagenic, co-carcinogenic, atherogenic and
toxogenic linked to liver cholestasis (gall stone blockage of the gall bladder) and the
Oxysterols (24, 25 and 27 Hydroxycholesterols). In particular premature babies are
associated with the at risk of high concentration of C-24 mono-hydroxy bile acids and
high Dietary Cholesterol maternal diets. [F14]
Esoterically as will be documented below and in Appendix A-1 because the human genome is encoded as a herbivore/vegan genetically, the human liver of the pre-natal, neonatal and infant processes any Dietary Cholesterol from the Mother's shared blood system or amniotic fluid as a slow poison through a Third Bile Acid Metabolic Pathway producing a unique mix of bile acids that persists from conception but is slowly transformed after birth by the development of intestinal flora until about 4 years of age when the "adult pattern" of cholesterol and bile acid metabolism dominates.
3.) US Maternal Mortality Rate (MMR) at 13.3% (per 100,000 live births) as reported in 2006 by the
UN World Health Organization up from 7% in 1996 places America 41st in industrialized
countries with Japan's MMR of 7.3% and 3 rd amongst industrialized nations. The MMR
amongst African Americans at 36.5% is genocidal! The last 10 years has seen a nearly
100% increase.
4.) As of 2006 America ranked 42 nd in Life Expectancy (LE) with 41 countries with longer LE's
than the US's 77.7 years with Japan's 81.5 years the leader amongst industrialized nations.
5.) Amongst those who die in America and their bodies undergo autopsies it is found on average
that in 50% of the major non-cancer causes of death in America the deceased also suffered
from a simultaneous incidence of cancer. Table One further details this bizarre situation.
Note: This "background noise" of Cancer can easily be discerned and understood from a
study of the DCRDS Systems Analysis Body Flow Chart to be presented below in
Section IV.
6.) Iatrogenic Disease (Doctor & health care Industry caused illness) is the "actual" #3 killer of
Americans after the #1 killer of Heart Diseases and #2 killer the Cancers with an
underestimated 250,000 deaths annually. Table One further details this. [D3]
7.) There were an estimated 200,000 bankruptcies in America in 2008 due to Iatrogenic
Poverty; i.e. from health care related bills as well as morbidity suffering from DCRDS.
8.) Iatrogenic Poverty Deaths is estimated at 45,000 a year amongst uninsured adults]. [D15]
9.) The sudden appearance over the last 30 years of Metabolic Syndrome (Met S.) affecting over
20% of Americans can involve simultaneously 9 risk factors for overweight and obesity,
diabetes mellitus Type II, hypertension, and cardiovascular heart disease.
Etiological suspect are the coinciding increased Dietary Cholesterol containing modern
American high animal protein and fat fast food diet, and the extensive use of blood
cholesterol lowering prescription drugs most notably the statins targeting decreasing
the livers natural production of Endogenous Cholesterol. [D 10]
Note: The 9 risk factors of Metabolic Syndrome cited above are:a.) increased waist circumference,
b.) elevated blood triglycerides,
c.) low blood HDL cholesterol,
d.) high blood LDL cholesterol,
e.) high blood uric acid,
f.) high blood pressure,
g.) fasting blood glucose,
h.) increased blood coagulation,
i.) in women high androgen levels, and
j.) in men high estrogen levels.
C. Esoteric Existence of Iatrogenic Disease and Iatrogenic Poverty Morbidity and Mortality
In 1975 the Austrian philosopher and Roman Catholic Priest Ivan Illich's iconoclastic and best
selling book entitled Medical Nemesis was released and shocked the American public with the
esoteric concept fully statistically documented of "Iatrogenic Disease" caused by the allopathic
health care industry of America.
Dr. Barbara Starfield, MD, PhD is an internationally recognized MD. and Public Health PhD.
teaching at the Johns Hopkins School of Hygiene and Public Health in Baltimore, MD. She has
further quantified what Ivan Illich warned of over two decades earlier as to the dangers of
"Iatrogenic Disease." Dr. Starfield courageously documented in her July 26, 2000 Journal of
the American Medical Association (JAMA) article "Is US Health Really the best in the world?"
that allopathic MD caused Iatrogenic Disease (MD's and their health care industry caused
deaths) resulted in 250,000 deaths and was the "actual" number 3 killer of Americans behind
#1 Heart Diseases and #2 the Cancers in 2000 as follows:
106,000 __ non-error, negative effects of drugs
80,000 __ hospital infections
45,000 __ other hospital errors
12,000 __ unnecessary surgery
7,000 __ hospital medication error
______Total Iatrogenic Disease Deaths 250,000
It is contended that nothing has changed for the better in the American health care system since 2000 and that Iatrogenic Disease remains as the "actual" number #3 killer in America in 2006 up to the present time in 2010 with an average 250,000 deaths annually.
The concept of "Iatrogenic Poverty" was first used in an editorial of that title by Bruno Meessen,
et al, Tropical Medicine and International Health, 8 (7) 581- 4, July, 2003 included herein as
Appendix B. Iatrogenic Poverty encompasses health care bills driving the patient and family into poverty financial failure including asset mortgaging, liquidation and bankruptcy. People of all
classes and in industrialized and developing countries as well are suffering the hardships from morbidity and mortality particularly from the Iatrogenic Poverty of the DCRDS:
"Poverty and illness are intertwined. It is a well documented fact that
poverty leads to ill health. In every society, morbidity and mortality
are higher amongst the poor."
The Dr. Andrew P. Wilper, MD., MPH, et al article "Health Insurance and Mortality in U.S. Adults" published on line and printed in the American Journal of Public Health, Vol. 99, Issue 12,
December, 2009 determines that there are on average 45,000 deaths annually amongst uninsured individuals and serious morbidity levels compared to insured individuals; i.e. Iatrogenic Poverty Deaths. Using national health survey data from 1984-1994 data for 3 chronic diseases and
syndromes _ diabetes, hypertension and high cholesterol __ which our sickness treatment epistemologically classified as DCRDS.
Dr. Wilpers research team found:
a.) 46% of the uninsured with diabetes never received a diagnosis for it compared
to 23% of those insured;
b.) 52% of the uninsured with high Cholesterol never knew they had the condition
compared to 30% of the insured;
c.) 78% of the uninsured with elevated Cholesterol were not in control of it
compared to 60% of the insured; and
d.) 58% of the uninsured with high blood pressure did not know it compared with
51% of the insured.
This study's co-author Dr. Steffie Woolhandler, MD., Professor of Medicine at Harvard University and
a primary health care physician in Cambridge, Mass. astutely noted:
"Historically, every other developed nation has achieved universal health care through
some form of nonprofit national health insurance. Our failure to do so means that all
Americans pay higher health care costs, and 45,000 pay with their lives.
This study declares the uninsured, working-age Americans have a 40 percent higher risk of death
than their privately insured counterparts, up from a 25 percent excess death rate found in 1993.
D. The "Background Noise" of the Cancer Epidemic
As presented above in Section III. B. 4 amongst those who annually die in America and their
bodies undergo autopsies it is found on average that in 50% of the non-cancer leading causes of death in America the deceased also suffered from a simultaneous incidence of cancer that did
not kill them.
Esoterically, this "background noise" of Cancer can easily be discerned as the allopathic health
care industry's institutional control of the statistics of the Cancer epidemic with its "root-cause"
intermixed in the 70 year suppression of "the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism."
This can be clearly seen and understood from a study of the DCRDS Systems Analysis Body
Flow Chart to be presented below in Section IV. By extrapolating this statistical "non-killing
cancer incidence" in those who die annually from one of the other TFK's, we can get a better
esoteric full picture of the "Cancer background noise" ___ the "hidden part of the iceberg" of
the systemic cancer epidemic that has gripped America as follows:
1996 ___ there were 539,323 Americans who died of Cancer.
___ there were 690,000 Americans who died of a TFK
other than cancer but also had Cancer.
2000 ___ there were 552,988 Americans who died of Cancer.
___ there were 701,036 Americans who died of a TFK
other than cancer but also had Cancer.
2006 ___ there were 559,801 Americans who died of Cancer.
___ there were 682,373 Americans who died of a TFK
other than cancer but also had Cancer.
E. The Top Fifteen Killers (TFK) of Americans in 1996, 2000 and 2006
It is hereby declared that the reality of the Top Fifteen Killing (TFK) Diseases__ defined herein as
taking the Leading Causes of Death in America and adding the esoteric existence of Iatrogenic
Disease mortality and Iatrogenic Poverty mortality __ reflect and encompass the effects of the
over 70 year suppression of "the great pathophysiological ramifications of dietary cholesterol
and bile acid metabolism" by the medical research, medical education and health care institutions
of the allopathic medical health care complex in America.
TABLE ONE: Leading Causes of Death in USA in 1996, 2000 and 2006: Top Fifteen Killers (TFKs)
of Americans compares the Top Fifteen Killing Diseases in America (TFK's) in 1996, 2000 and in
2006. TFK's are defined as taking the Leading Causes of Death in America and adding estimated
levels of the esoteric existence of Iatrogenic Disease and Iatrogenic Poverty mortalities.
Please note there exists in Table One a big difference in the number of deaths between the #2
TFK of Cancer and the #3 TFK of Stroke. This is theorized as a statistical manifestation of the suppression of the great ramifications of dietary cholesterol and bile acid metabolism as will
become more and more clear further within the Web Page.
IV. The Etiology of the Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)
A. Dietary Cholesterol is not a Dietary Requirement
Magills Medical Guide, edited by Tracy Irons-Georges, [Salem Press, Inc. 2005, 3 rd revised
edition] Volume I, pages 492-293 declares with emphasis added:
"The body can meet its needs for cholesterol through synthesis; there is no dietary
requirement. Cholesterol deficiency does not arise in humans even on a purely
vegetarian [cholesterol free (herbivore/vegan)] diet. &. The liver is the most
important site for cholesterol synthesis within the body &. Mammalian cells have
the capacity to synthesize their own cholesterol."
Yes, there is no scientific basis nor nutritional need for humans to ingest animal flesh and
violate the aboriginal human nutritional directive presented in the FIRST LAW presented in the
Bible Genesis 1: 29 as the herbivore/vegan diet except for metaphysical and cultural socio-
political economic reasons. Ironically, as the human body treats an organ transplant as a large
foreign source of antigens and rejects it so it does with Dietary Cholesterol: Consequently, the
"great ramifications of dietary cholesterol and bile acid metabolism" of breaking the FIRST LAW
is the Omnivores Dilemma which a priori does not significantly occur in the Herbivore/Vegan diet.
B. Stereoisomer Specificity & Organic Steroid Chemistry of Cholesterol:
Natural-Cholesterol (5 cholesten 3-beta-ol)
Above is the "three dimensional" steroid stereoisomer chemistry and steroid molecule numbering
of the 27 Carbon atoms of the "generic" Cholesterol molecule used for both:
i.) human Endogenous Cholesterol made mostly by a specific human's live
and to a lesser extent made by each of its cells; andii.) the isomer Dietary Cholesterol sourced from the ingestion of animal "pseudo" food by Omnivore Diet humans.
Knowledge of the Cholesterol molecule's steroid stereoisomer chemistry and steroid molecule numbering is necessary to uncover and understand the primary etiological role of Dietary
Cholesterol in the chronic diseases and syndromes suppressed by the Omnivore Diet connected
Food Industry and the Health Care Industry Special Interests who profit from it. By scientific convention the Cholesterol molecule lies on the plane of the paper and the positions C
(carbon atom) 18 and C19 show a solid cone or beta-configuration as they lie above the
plane of the paper while the positions H (hydrogen atom) 28 and H30 show the striated cone or alpha-configuration below the plane of the paper.
Above in "two dimentions" are shown the 8 stereocenters of the cholesterol molecule indicated
as circles. It reveals why each specific individual of each animal species on earth which makes cholesterol including that of the mammalian vertebrate species of humans (homo sapien) makes
a cholesterol molecule isomer that is unique to that specific animal species individual. Since it
has 8 stereocenters it will thus have 2 to the 8th power or 256 possible isomers.
Note: The generic Cholesterol molecule is an aromatic polycyclic with a C5-C6 double bond.
Specifically, the Cholesterol molecules of a unique human's natural Endogenous Cholesterol or Natural-Cholesterol have the following organic steroid chemistry stereoisomer specificity:
1.) IT CAN NOT BE SUBSTITUTED with molecules of a different humans Endogenous Cholesterol; and
2.) NOR CAN IT BE SUBSTITUTED by the Dietary Cholesterol from butchered, cooked animal meat or rennet based dairy products WITHOUT a varied and holistic full body immune system response.
The "ramification symptoms of breaking the FIRST LAW" is similar to that of the transplanted organ/tissue rejection with inflammatory blood and white cell tissue markers and antibodies
produced by the antigen Dietary Cholesterol. Thus are manifested the Omnivore Diet's being
associated with the "autoimmune diseases" of atherosclerosis (hardening of the artery),
diabetes mellitus and Alzheimer's disease (AD) and most all non-alcoholic human dementia. Consequently, the AD dementia produced by "senile" placques originate from mutagenic clone
white blood cells secreting amyloid muco-fibroid-protein.
Again take note: That the generic cholesterol molecule is a steroid with an aromatic polycyclic
with an unsaturated, double carbon bond at the C5-6 positions hydrocarbon structure.
The nat-Cholesterol, ent-Cholesterol and epi-Cholesterol isomers are:
1.) The Human molecule of Natural (Endogenous) Cholesterol
(Nat-Cholesterol, 5 cholesten 3- beta-ol)
Nat-Cholesterol (Natural-Cholesterol, 5 cholesten 3- beta-ol)
It is theorized herein that Human Endogenous Nat-Cholesterol has an isomer twin within
the Animal/Dietary Cholesterol of the mammalian beef, pig, lamb and goat meat and dairy
products as well chicken and other avarian, fresh and salt water animal "pseudo" foods of
Omnivore Diet and dairy products of the Vegetarian Diet. These diets by a priori definition
will cause a cholesterol antibody immune reaction.
Note: Human Endogenous Nat-Cholesterol being synthesized by a specific human's liver
will not cause an antigen Dietary Cholesterol antibody immune reaction.
2.) The enantiomer Ent-Cholesterol (5 cholesten 3-alpha-ol)
Ent-Cholesterol (5 cholesten 3-alpha-ol)
This mirror image isomer of Nat-Cholesterol has the exact chemical composition and properties does possess the same cell membrane component electro-magnetic display in reverse, the same physical properties and similar biological and chemical reactions as does Natural (Endogenous) Cholesterol.
It is theorized herein that Ent-Cholesterol is a major isomer component of the Dietary Cholesterol acquired from mammalian beef, pig, lamb and goat meat and dairy products as well chicken and other avarian, fresh and salt water animal "pseudo" foods of the Omnivore Diet and dairy products of the Vegetarian Diet.
Note: In vivo tissue culture research indicates that Ent-Cholesterol can support cell growth during the first generation. However, cell death results in generation two reflecting that
the necessary mitosis proteins and enzymes being enatiomer selective need the Nat-Cholesterol stereochemistry configuration. [F. 36]
Note: Ent-Cholesterol will cause a antibody immune reaction if ingested by a human whose body treats Dietary Cholesterol as an antigen.
3.) The epimer Epicholesterol [5 cholesten 3-alpha-ol]
This epimer isomer of Nat-Cholesterol although of exact chemical composition and properties does not possess the same cell membrane component electro-magnetic display, physical properties and biological and chemical reactions as does Natural (Endogenous) Cholesterol.
It is theorized herein that 3 alpha- Epicholesterol is a major isomer component of the Dietary Cholesterol acquired from mammalian meat and dairy products as well avarian, aquatic animal
"pseudo" foods that Omnivores and dairy products Vegetarians are consuming.
Note: Epicholesterol will cause an antibody immune reaction if ingested by a human whose
body treats Dietary Cholesterol as an antigen.
Epicholesterol (3 alpha-epimer isomer) [5 cholesten 3-alpha-ol]
Note: In vivo tissue culture research indicates that epicholesterol can not support cell
growth during the first generation leading to cell death results reflecting that the
necessary cell membrane generation involving non-enatiomer selective lipids need
the nat-Cholesterol stereochemistry configuration. [E. 15]
It is important to note herein that a distinction is made in the cancer etiological language used
between mutagenic and carcinogenic agents be they inorganic chemical, organic (hydrocarbon) chemical, biochemical, viral, electromagnetic or radioactive in nature:
a.) mutagenic agents cause DNA chromosomal nucleotide base changes to a specific cell producing various phenotype abnormalities including in the case of cancer neoplasmic appearance and behavior that is passed on in that cells gene meiosis and mitosis; and
b.) carcinogenic agents promote the growth, survival and spread of neoplasmic cancer cells.
Note: 1.) That the polycyclic aromatic biochemical steroid Cholesterol and its Bile Acid
derivatives are suspect as and can be both mutagenic and/or carcinogenic agents.
2.) That the polycyclic aromatic hydrocarbon chemicals like benz(o)pyrene can be
both or singularly mutagenic and/or carcinogenic agents.
C. Colorectal Cancer Cause Identified & Connected to America's High Fat Diet
In 1974 the ground breaking article was published by T. Narisawa et al entitled Promoting
effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-
N- nitrosoguanidine in rats in the Journal of the National Cancer Institute, V. 53, pp. 1093
funded by the Great Britain National Institute of Health first connecting colorectal cancer to
bile acid metabolism. Specifically, this article was the first to document that the so-called secondary bile acid Lithocholic Acid (LCA) promoted the known chemical mutagenic and carcinogenic agent called N-methyl-N'-nitro-N-nitrosoguanidine.
Thus by our definition and the authors T. Narisawa et al so cited LCA is a co-carcinogenic
agent.
Note: This article was obviously missed by the definitive milestone findings of the
US Senate Select Committee on Human Nutrition and Human Needs convened
by US Senator George McGovern released 2 years earlier by the US. Government
Printing Office (GPO) in 1972.Fortunately, 25 years latter in 1999 Japanese medical scientists lead by Makoto Makishima,
PhD. Professor, Department of Biochemistry, Nihon University School of Medicine, Tokyo,
Japan observed the comparative epidemiological data of red meat ingestion between Japan
and America and the higher incidence of colorectal cancer in the latter. He was funded to
do research at the University of Texas Southwestern Medical Center in another area of cholesterol and bile acid metabolism, that of Vitamin D3 which is made in the human body
from a precursor from Endogenous Cholesterol.
Makishima's work was reported in an article in the Science Magazine, May 17, 2002 issue entitled "Vitamin D Receptor as an Intestinal Bile Acid Sensor."
Dr. Makoto Makishima's own research confirmed that Dietary Cholesterol was catabolized in the human liver into the so-called primary bile acid Chenodeoxycholic acid (CDCA), and that CDCA was in turn transformed by anaerobic pathogenic bacteria in the human colon into the so-called "secondary bile acid" Lithocholic Acid (LCA). LCA's role in causing the number 2 death causing cancer site of colorectal cancer in America cannot be denied. The University of Texas Southwestern Medical Center Press Release on Makishima's article in the Science Magazine cited above and the article itself are attached as Appendix C.
Consequently, since 1974 the "secondary bile acid" LCA has been identified as the most powerful biochemical carcinogenic agent known to science. Although it is not mutagenic it is toxic to the liver whose prime directives include detoxification of poisons; it is toxic to the pancreas, spleen, heart, lungs and kidneys; and additionally holistically promotes the growth and spread of already existing cancer cells (neoplasms) and thus is carcinogenic.
With both humans and most domesticated animals being mammals, animal meat is similar to human flesh. For a human who genetically is like the mouse a herbivore [not like the rat and
pig who are genetically omnivores] the biggest problems of eating mammalian animal meat
are the ramifications to the human body of "mammal cannibalism." The human body as a genome herbivore can not fully digest the "pseudo food" of animal meat which is composed
of but not limited to the following animal biochemical elements that are human diet unnatural and antigenic in the body:
a.) muscle tissue made up of cell membranes of Dietary Cholesterol, fatty acids, the 20
protein amino acids especially cystein, methionine, glycine and tryptophane and
with myolin and actin fiber proteins which allow it to contract and the neuroproteins
of DNA and RNA of cellular nuclear encased genetic material;
b.) muscle nerve tissues which is made up of cell membranes of Dietary Cholesterol, fatty acids, the 20 "essential" protein amino acids especially cystein, methionine and glycine and tryptophane; myelin fiber protein phospholipids and the neuroproteins of DNA and RNA of the nerve cell's nuclear encased genetic material;
c.) blood vascular tissue made up of cell membranes of Dietary Cholesterol, fatty acids, the 20
protein amino acids especially cystein, methionine and glycine and tryptophane; the
neuroproteins of DNA and RNA of the nerve cell's nuclear encased genetic material and red
and white blood cells and their components; and
d.) connective tissue and intracellular mucopolysaccharrides.
The Medical Sciences since Professor Makoto Makishima's 2002 Science Magazine article have
continued to try and avoid implicating Dietary Cholesterol in the etiology of colorectal cancer. Predictably they have and are trying to apply therapeutic pharmacological techniques to control the underlying chronic enteric toxemic infection producing the Secondary Bile Acids and their further bacterial degradation to Tertiary Bile Acids. Especially of concern here are the anaerobic pathogenic Clostridium bacteria which are capable of Nuclear Dehydrogenation (HDH) of the A-ring of the
steroid bile acid structure to a 4-ene-3 one configuration. As polycyclic aromatic hydrocarbons this makes these transient Tertiary Bile Acids suspect as highly mutagenic and carcinogenic.
The quandary faced by colon cancer researchers in this cited environment of decades of special
interest medical institutional and industrial cancer etiological knowledge suppression of colorectal cancer's cause is epitomized by Bandaru S. Reddy, DVM, PhD. and Ernest L. Wynder, MD. In their
1977 astute article "Metabolic Epidemiology of Colon Cancer: Fecal Bile Acids and Neutral Sterols
in Colon Cancer Patients and Patients with Adenomatous Polyps" in the (British) Journal of Cancer,
39, pp 2533-39, 1977 Reddy and Wynder analyze the quandary as follows:
"The increased enzyme activities of the fecal flora to produce secondary bile acids
and cholesterol metabolites coupled with increased fecal excretion of bile acids and cholesterol metabolites in colon cancer patients compared to controls raises the intriguing possibility of their role in the etiology of colon cancer. The possibility
exists that fecal bacterial 7 alpha-dehydroxylase and fecal cholesterol and its metabolites, and [the so-called "Secondary Bile Acids"] lithocholic acid (LCA)
and deoxycholic acid (DCA), could be utilized as metabolic indicators that will
reflect high and low risk populations as well as patients withn colon cancer. The question may be raised as to the extent to which the findings of this and other
studies provide (to) causative explanation to human large bowel [colon] cancer."
"Although a specific carcinogen for the colon has not been identified in the feces,
an association has been established between colon cancer and fecal excretion of
bile acids and cholesterol metabolites."
"The questions that need to be answered are:
a.) whether carcinogens are present in the colonic lumen or whether they
are synthesized by the colonic mucosa, and
b.) how the bacterial metabolites act and/or interact."
"In colon carcinogenesis, as is also likely in other forms of chemical carcinogenesis, factors that modify the action of carcinogenesis may not only play a predominate
role in intervention, but also have crucial preventative significance."
"From a prevention point of view, studies are required to investigate the dietary
changes that can alter the composition and concentration of intraluminal bile
acids and/or cholesterol metabolites."
From 1920 to 1930 Professor Hieger and his teacher Professor E. L. Kennaway at the Cancer
Hospital Research Institute, London, England, GB. pioneered the study of carcinogenic
organic (hydrocarbon) chemicals. They were the first to isolate and prove the main
carcinogenic agent in coal tar and cigarette smoke was the polycyclic aromatic (unsaturated
carbon double bond) hydrocarbon chemical 3:4-Benz(a)pyrene, which as part of asbestos is
a major occupational and environmental cancer vector.
3:4-Benzo(a)pyrene
Professors E. L. Kennaway and Israel Hieger and their team discovered four attributes about hydrocarbon chemical mutagenic carcinogens as follows:
a.) the mutagenic carcinogenic chemicals are polycyclic aromatic hydrocarbons made up of condensed or unsaturated double carbon bond rings;
b.) when many substances containing hydrocarbon chemicals are exposed to high heat they become carcinogenic chemical tars and oils;
c.) when suspected mutagenic carcinogenic chemicals are exposed to ultra-violate light
they give off a fluorescent spectrum of 3 fluted bands at 4000, 41800 and 4800
Angstroms measurable with a spectroscope; andd.) when suspected carcinogenic chemical are tested by subcutaneous injection into
laboratory mice it produces sarcoma tumors (mostly sarcomatoid carcinomas) at
the point of injection with control groups tested without the substance being tested used.
Professors Hieger and Kennaways carcinogenic search and test procedure was as follows:
1.) high temperature heating various tars and oils and transforming other substances via high heat into a tar or oil;
2.) ultra-violate light fluorescent spectrum testing them for the 3 characteristic carcinogen
fluted bands at 4000, 41800 and 4800 Angstroms; and
3.) systematically testing suspect substances for their mutagenic and carcinogenic abilities
by subcutaneously injecting laboratory mice under stringent controls seeking
confirmation by sarcoma tumor production.
In 1930 Professor Hieger published the results of his ongoing research for other carcinogenic
chemicals at the Cancer Hospital Research Institute in 2 scientific journal articles that tested over
60 tars, oils and other substances as follows:
a.) E. L., Kennaway and Izrael Hieger, I, "Carcinogenic Substances and their Fluorescence Spectra," British Medical Journal, pp. 1044 46, June 7, 1930
b.) Izrael Hieger, "The Spectra of Cancer Producing Tars and Oils and Related Substances,"
Biochemical Journal, V. 24 (2) pp. 505- 61, 1930
Incredibly, Professor Izrael Hieger conclusively demonstrated in these 2 scientific journal articles
that Dietary Cholesterol Tar as well as Dietary Animal Meat Tar were mutagenic carcinogens.
Note: This does not portend well for the subject of the carcinogenesis of cooked animal meats to
be dealt with later in the forth coming Purple Paper on this subject. Cooking animal meat is
the only way most humans can stand to eat it and this is the aboriginal source of the origin
of cooked foods and meals. In particular the notorious mutagenic and carcinogenic
Benz(o)pyrene permeates charcoal grilled animal meat.
It is not a coincidence that Dietary Cholesterol meets all of Professor Hieger and Professor E. L. Kennaways observed characteristics of mutagenic/carcinogenic chemicals of:
a.) being an aromatic or cyclic biochemical made up of condensed or unsaturated double
carbon bond ring;
b.) that the Dietary Cholesterol Tar gave off the ultra-violate light fluorescent spectrum of
3 bands at 4000, 41800 and 4800; and
c.) produced sarcomas in laboratory mice.
After over 16 years of painstakingly careful basic research Professor Hieger [now at the Chester
Beatty Research Institute, Royal Cancer Hospital London, England, GB. partly funded by the US
Public Health Service] published 9 scientific journal articles starting in 1946 that conclusively
demonstrate that Dietary Cholesterol is both mutagenic as well as carcinogenic as follows:
1.) 1946 _ Izrael Hieger, "Carcinogenic Substances in Human Tissue,"
Cancer Research, V 6, pp 657- 67
2.) 1947 _ Izrael Hieger, "Carcinogenic Activity of preparations rich in Cholesterol,"
Nature, V. 160, pp 270- 71
3.) 1949_ Izrael Hieger, "Carcinogenic Activity of Lipoid Substances,"
Bri. Journal of Cancer, V. 3, pp 123-39
4.) 1954 _ Izrael Hieger and S.F.D. Orr, "On the Carcinogenic Activity of Purified Cholesterol," Bri. Journal of Cancer,
V. 8 (2), pp 274-90
7.) 1959 _ Izrael Hieger, "Carcinogenesis of Cholesterol," Bri. Journal of Cancer, V. 8 (3),
pp 439-51
Note: This journal article is attached as Appendix D.
8.) 1960 _ Izrael Hieger, (unknown article title)
Acta Unio Internationalis Contra Cancrum, V. 15, p. 603,
Geneva, Switzerland
Note: This article was so suppressed its Title is not retrievable on the Internet. Its paper journal resides on shelve in a few European University Libraries. The journal became defunct in 1964 and has not been digitized and no abstract of the article exists.
During this over 16 years of painstakingly careful basic research Professor Izrael Hieger, D. Sci.
used three formulated sources of human cholesterol utilized as dietary cholesterol when injected
into mice to study its simultaneous mutagenic and carcinogenic abilities as follows:
a.) an unsaponifiable 85% human cholesterol liver extract from humans who had died of cancer or died of other diseases;
b.) a commercial human cholesterol source; and
c.) a purified 100% human cholesterol preparation provided by a pharmaceutical manufacturing company further purified.
Professor Izrael Hieger, D. Sci. under total environmental carcinogenic free laboratory conditions
and a controlled research model showed that these 2 Dietary Cholesterol formulations were
slow acting up to 19 months latent mutagenic and carcinogenic agents as follows:
1.) mice subcutaneously injected with the unsaponifiable 85% human cholesterol liver extract produced sarcomas at rates as high as 6%; and
2.) mice subcutaneously injected with a purified 100% human cholesterol preparation
provided by a drug manufacturing company produced sarcomas at rates as high as 14%.
Note: Unsaponfiable means that all fats have been removed from the substance with
the use of alcohol basic solvent(s) used to make soaps and no fatty acids, triglycerides or phospholipids remain.
The 1959 above cited Izrael Hieger British Journal of Cancer article is attached as Appendix D.
Observe that 2 strains of laboratory mice which are herbivore mammals where injected with mammalian human cholesterol. Thus Professor Hieger's in vivo research mouse model using our cancer etiological language distinctions presente above was testing Dietary Cholesterol and not Endogenous Cholesterol as a mutagen and a carcinogen; i.e. the mice as herbivore mammals were forced by injection to be mammal cannibals.
Thus in 1977 unbeknownst to Professor Bandaru S. Reddy and Ernest L. Wynder, the aromatic (unsaturated) polycyclic Dietary Cholesterol had already been scientifically identified in 1959 as the specific colonic carcinogenic chemical not only in colon feces, but in the blood stream and systemically in the entire human body of those humans eating an Omnivorous Diet. The association between colon cancer and fecal excretion of bile acids and cholesterol metabolites identified by
Reddy and Wynder is now readily explainable with Dietary Cholesterol identified as a colon cancer mutagen and carcinogen for those eating an Omnivorous Diet.
Professor Izrael Hieger, S. Sci.s research definitively proving that Dietary Cholesterol was mutagenic and carcinogenic has been suppressed. After his 1961 book review of cancer theories
Carcinogenesis (160 pages) published by Academic Press, Inc., London, England where he includes Dietary Cholesterol as carcinogenic he is credited with one more journal research on carcinogens in 1965.
Esoterically, the a specific human's ingestion of the slow poison Dietary Cholesterol causes their
Liver to make the primary bile acid Chenodeoxycholic acid (CDCA) as a detoxification product.
The Liver detoxifies CDCA by conjugating it with the amino acid glycine or the sulfonic acid
taurine and dumps the resulting bile salts into the Gall Bladder as detoxed excretory products.
Fortunately, another cancer researcher in London, England bacteriologist Vivienne C. Aries, PhD.
(St. Marys Hospital Medical School) from 1969 through 1973 exploring the association of colorectal cancer with industrial countries again albeit Japan. This led her to explore in particular the dietary cholesterol and bile acid metabolism of 1.) industrial urban English people compared with
agricultural rural people of Uganda; and 2.) humans on the Omnivore diet as compared with those
on a strict Vegetarian diet.
Characteristically, humans on a Omnivore Diet will have unsanitary chronically infected colons reinforced daily by their eating more animal meat flesh and organs containing the pathogenic anaerobic bacteria. The resulting chronic toxemic infections in their colons allows these pathogenic anaerobic bacteria to deconjugate the bile salts neutralizing their Livers detoxing. From further bacterial putrefaction the un-conjugated CDCA is degenerated into the carcinogenic agent the so-called secondary bile acid Lithocholic Acid (LCA).
Professor Vivienne C. Aries verified that the 3 major fecal pathogenic anaerobic bacteria as Bacteroides, Enterobacteria including E. Coli and Clostridia Bacteria for humans on the Omnivore Diet and on a strict Vegetarian Diet possessing and using the 7-dehydroxylase enzyme required to degrade the Primary Bile Acids Cholic Acid (CA) and Chenodeoxycholic acid (CDCA) respectively into the so-called Secondary Bile Acids Deoxycholic acid (DCA) a weak carcinogenic and Lithocholic acid (LCA) is a strong carcinogenic.
Professor Aries also discovered [Aries, VC, and Hill, M.J. "Degradation of Steroids by Intestinal Bacteria II", Biochem, Biophys Acta, V. 202, pp. 535, 1970 as reported in op cit, 1971] that the Bacteriodes bacteria found in the human Omnivores gut degradee Bile Acids greater than those found in the human Vegetarian's gut:
i.) That Bacteriodes spp. of Omnivores have 49% of the 7-dehydroxylase enzyme; and
ii.) That Bacteriodes spp. of strict Vegetarians have only of the 20% 7-dehydroxylase enzyme.
TABLE TWO details the findings from Professor Vivienne C. Aries, et al, "The Effect of a Strict Vegetarian Diet on the Faecal Flora and Faecal Steroid Concentration", British Journal of Pathology,
V. 103, pp. 54-56, 1971. The pattern that emerges of the fecal neutral steroids (Dietary Cholesterol and its bacterial metabolite coprostanol) and the primary and secondary bile acids in humans on various diets presented is summarized below:
1.) Omnivores have 1.4 times more Dietary Cholesterol and 1.7 times more Total Fecal
Bile Acids including 1.4 times more Fecal CDCA and 2.7 times more Fecal LCA than strict Vegetarians.
2.) Omnivores have 121 times more Dietary Cholesterol and 3.6 times more Total Fecal Bile Acids including 26 times more Fecal CDCA and 27 times more Fecal LCA than Vegans (Herbivores).
Observe Dietary Cholesterol is predictably mutagenic and carcinogenic being a polycyclic aromatic
but that its detox excretory derivative made by the liver the Primary Bile Acid of CDCA and its bacterial degradation product the so-called Secondary Bile Acids LCA are only partially detoxed to carcinogenic.
TABLE THREE below presents an inventory of scientifically confirmed mutagenic, carcinogenic, artherogenic, cholestagenic (gallstone formative) and toxogenic agents in the etiology of colorectal and other cancers, cardiovascular, stroke and other Dietary Cholesterol and Related Diseases and Syndromes. Please take note there are 28 substances so inventoried which are dietary cholesterol or derivatives from it produced in the body by various organs, spontaneously or by pathogenic bacteria!
Tertiary Bile Acids are short lived and hard to detect and are produced by the 3 major fecal pathogenic anaerobic bacteria Bacteroides, Enterobacteria and Clostridia. Especially dangerous are the "NDH ('A ring' Nuclear Dehydrogenating)" capable Clostridia (Lecithinase enzyme (-) negative) that form aromatic (unsaturated) cyclic structured Tertiary Bile Acids that by definition are suspected as mutagenic and carcinogenic. Thus in Toxemic colon conditions the Bacteroides Bacteria can degrade Dietary Cholesterol to a 3-alpha, 6-alpha dihydroxyl bile acid which in turn can be further metabolized by Lecithinase enzyme (+) positive Clostridia Bacteria to a 6 alpha-hydroxl-5 beta cholan-3 Oxo-24 oic acid and then converted by NDH capable Clostridia (Lecithinase enzyme (-) negative) into the known mutagenic and carcinogenic Tertiary Bile Acid 6-Alpha Hydroxychol-4 ene-3 -none oic acid.
The free Endogenous Cholesterol that the Liver excretes into the gall bladder and is released into the small intestines is degraded in the Toxemic colonic conditions by pathogenic anaerobic bacteria especially the 3 major fecal Bacteroides, Enterobacteria and Clostridia Bacteria in humans on the Omnivore diet and on a strict Vegetarian diet resulting in the following non-mutagenic and non-carcinogenic fecal Neutral Steroids:
a.) Endogenous Cholesterol (5 cholesten 3-beta- ol)
Note: Natural (Endogenous) Cholesterol by definition made in the host human body is not mutagenic nor carcinogenic in that body.
b.) coprostanol (5 beta cholestan 3 beta - ol) __ the main fecal steroid
c.) coprostanone (5 beta cholestan 3 one)
d.) triol (cholestane - 3 beta, 5 alpha, 6 beta -triol) __ weakly carcinogenic and toxogenic
However, any remaining Dietary Cholesterol [that escapes being converted by the Human Liver to
the toxic Primary Bile Acids CA and CDCA and further detoxification mostly to their glycine and a taurine conjugated Bile Salts them mostly to] in the Toxemic colonic conditions [of the predominate
3 fecal pathogenic anaerobic bacteria Bacteroides, Bifidobacteria and Clostridia in humans on the Omnivore diet and strict Vegetarian diet] is catabalized into cholestenone (4 cholesten 3 - one). Predictably, since Cholestenone (4 cholesten-3 - one) as the result of the degradation action of the NDH clostridium Bacteria is a "4 ene - 3 one" class or aromatic cyclic steroid, it is a suspected carcinogenic. Indeed as indicated in TABLE THREE in vitro animal studies have confirmed that cholestenone is a mutagenic and carcinogenic. [F. 17]
Please note that the isomers of Dietary Cholesterol both "Natural Cholesterol_ 3 Beta" and "Enantiomer Cholesterol_ 3 Alpha" are major mutagenic carcinogens in human colorectal cancers.
The Medical Sciences and Organic Steroid Chemistry are corrupted by promulgating the falsehood
that the human liver metabolizes Endogenous Cholesterol into the Primary Bile Acid C-24, 3-alpha CDCA and 3-Beta-5-Cholenoic acid; when in fact ONLY Dietary Cholesterol is the source of the
C-24 3-Beta and 3-Alpha Bile Acids and isomers of CA, and CDCA with the intestinal Toxemic
bacteria degrading them to DCA and LCA respectively.
D. Secrets of Dietary Cholesterol and Bile Acid Metabolism
In 1976 It is important to note that 2 years after T. Narisawa's ground breaking 1974 article
associating the "secondary bile acid" LCA with colon cancer, Professor D.P. Burkitt, PhD. an
external staff of the British Medical Research Council published another ground breaking
article entitled "The Etiological Significance of Related Diseases" in the Canadian Family
Physician Journal, V. 22 (999) pp 64-71. He discloses that his 40 years of clinical medical
experience and 3 year questionnaire investigation of hospital staff in developing countries
had lead to the hypothesis that the following diseases "among the prevalent complaints in
the western world today are closely associated with one another" and that they "share some
common causative factor" as follows:
a.) Ischemic heart disease
b.) Gallbladder disease
c.) Appendicitis
d.) Diverticular disease
e.) Colorectal cancer
f.) Hemorrhoids
g.) Varicose veins
h.) Hiatus herniai.) Obesity
j.) Diabetes
The common cause Professor Burkitt identified was the lack of dietary fiber in the modern
Western diet. Clearly, in hindsight he almost figured out the DCRDS and their common cause.
Surely the use of the refined carbohydrates we call the "5 white foods" of white flour, white
sugar, white table salt, white rice and rennet containing dairy products is a secondary factor
with constipation being the common symptom. Everyone knows animal meat is without any
significant fiber and constipating.
Please find attached the Dietary Cholesterol Related Diseases and Syndromes (DCRDS)
Systems Analysis Body Flow Chart for a composite relational and causative picture of the
"great pathophysiological ramifications of bile acid metabolism." The DCRDS Systems
Analysis Body Flow Chart is hand scribed and 5 color coded for ease of navigational
reading and systems synthesis simulation as follows:
* green for the 9 step Food Ingestion, Digestive and Elimination System;
* yellow for organs;
* red for the blood stream;
* blue for "bile acid metabolism;" and
* orange for a member of the Top Fifteen Killing Diseases of Americans (TFK's) in 2006.
For those reading a flow chart for the first time it is made up of "Analysisof Systems" basic building
blocks of the "subsystem components" themselves composed of the followng 3 elements:
a.) an input arrow to "b.) the process;"b.) a square or rectangular shaped "process (like an organ);" and
c.) an output arrow leaving "b.) the process."
"Everything is everything" and so in the world and universe viewed from the perspective of
Systems Analysis anything can be accurately so described and simulated via Systems
Analysis protocol.
From the synthesis of in vitro and in vivo primary health research and epistemological/observational research the simulation of the DCRDS Systems Analysis Body Flow Chart deduces that Thirteen (13)
of the Top Fifteen Killing (TFK) Diseases in America in 2006 can be identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS).
TABLE FOUR: Thirteen of Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and
Related Diseases and Syndromes (DCRDS): Results of the DCRDS Systems Analysis Body Flow Chart presents these synthesis simulation deduction results.
Specifically, it is herein declared that it has been documented and simulated by the DCRDS Systems Analysis of the Human Body Flow Chart that thirteen (13) of the Top Fifteen Killing (TFK) Diseases in America in 2006 can be identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS) caused by Dietary Cholesterol and its associated Animal Protein and Animal Fat residues from the American high fat/high protein modern refined food Omnivores Diet particularly from the fast food venues as follows:
#1. Heart Diseases
#2. the Cancers
#3.' Iatrogenic Disease (physician/health care system caused)
#3. Stroke
#4. Asthma/Emphysema/Bronchitis
#6. Diabetes Mellitus
#7. Alzheimer's Disease
#8. Influenza/Pneumonia
#9. Kidney Diseases
#9'. Iatrogenic Poverty
#10. Septicemia
#11. Suicide
#12. Liver Diseases
#13. Hypertension
#14. Parkinson's Disease
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